Table 4. Odds ratios (OR) for cognitive impairment according to IGF-I tertiles in females and males.

Model	IGF-I Tertile 1 OR	IGF-I Tertiles 2 and 3 Reference OR	p-value
Females
	n=55	n=108
Model A: Unadjusted (n=163)	0.39 (0.19-0.82)	1	0.01
Model B: Adjusted for age (n=163)	0.39 (0.19-0.83)	1	0.01
Model C: Adjusted for age, diabetes, hypertension, cancer, cardiovascular disease (n=148)	0.42 (0.19-0.97)	1	0.04
Model D: Adjusted for age, depression, education, tobacco use, alcohol use, and IGFBP-3 (n=104)	0.24 (0.06-0.98)	1	0.047
Males
	n=14	n=26
Model A: Unadjusted (n=40)	2.09 (0.36-12.08)	1	p=0.41
Model B: Adjusted for age (n=40)	2.47 (0.40-15.09)	1	p=0.33