Table 1. Association between miR-346 and baseline characteristics.
| Parameter | n | miR-346 expression | ||
|---|---|---|---|---|
| Low(n=38) | High(n=76) | P-value[a] | ||
| Age(years) | <0.0001[*] | |||
| ≤ 60 | 45 | 26 | 19 | |
| > 60 | 69 | 12 | 57 | |
| Sex | 0.8938 | |||
| Male | 50 | 17 | 33 | |
| Female | 64 | 21 | 43 | |
| Differentiation | 0.0873 | |||
| Well, moderate | 36 | 8 | 28 | |
| Poor | 78 | 30 | 48 | |
| Tumor size (maximum diametercm) | 0.0061[*] | |||
| ≤ 3cm | 32 | 18 | 18 | |
| > 3cm | 82 | 20 | 62 | |
| Smoking | <0.0001[*] | |||
| Yes | 83 | 15 | 68 | |
| No | 31 | 23 | 8 | |
| Lymph node metastasis | 0.0119[*] | |||
| Positive | 76 | 17 | 59 | |
| Negative | 48 | 21 | 27 | |
| TMN stage | 0.0140[*] | |||
| I | 21 | 12 | 9 | |
| II/III/IV | 93 | 26 | 67 | |
| Histological tumor type | 0.5658 | |||
| Squamous cell carcinoma | 79 | 25 | 54 | |
| Adenocarcinoma | 35 | 13 | 22 | |
Chi-square test
P< 0.05