Table 1.
Description of the FSE cohort at baseline
| FSE cases (N=214) | Simple FS controls (N = 102) | |
|---|---|---|
| Mean age (months) (SD) | 20.2 ± 12.7 | 22.0 ± 10.6 |
| Median age (months) (IQR) | 15.8 (12.0 – 23.2) | 19.7(15.8 – 25.03) |
| Sex (%) | ||
| Male | 111 (51.9) | 59 (57.84) |
| Female | 103 (48.1) | 43 (42.16) |
| Mean duration of febrile seizure (min) | 87.7 (70.1) | 22.0 ± 10.6 |
| Median duration of febrile | 70.0 | 3.00 |
| seizure (IQR) (min) | (45.0-105.0) | (2.00 - 5.00) |
| Type of seizure (%) | ||
| Continuous | 121 (56.5) | 102 (100.00) |
| Intermittent without full recovery | 69 (32.2) | 0 (0.00) |
| Intermittent with drug therapy | 24 (11.2) | 0 (0.00) |
| Focal seizure (%) | ||
| Definitely | 148 (69.2) | 0 (0.00) |
| No (Generalized) | 66 (30.8) | 102 (100.00) |
| Definite cerebral lateralization (%) | ||
| Left | 38 (17.8) | 0 (0.00) |
| Right | 29 (13.6) | 0 (0.00) |
| No definite cerebral lateralization | 147 (68.7) | 102 (100.00) |
| Seizure classification (%) | ||
| Generalized tonic–clonic | 66 (30.8) | 102 (100.00) |
| Complex partial only | 4 (1.9) | 0 (0.00) |
| Partial with secondary generalization | 144 (67.3) | 0 (0.00) |
| Prior development (%) | ||
| Normal | 183 (85.5) | 100 (98.04) |
| Suspect | 13 (6.1) | 2 (1.96) |
| Abnormal | 18 (8.4) | 0 (0.00) |
| Baseline MRI findings (%) | ||
| Any definite abnormality | 140 (73.7) | 79 (89.77) |
| Increased T2 signal in the hippocampus | 50 (26.3) | 9 (10.23) |
| HIMAL (%) | ||
| No | 140 (89.2) | 79 (97.53) |
| Yes | 17 (10.8) | 2 (2.47) |
| HHV6 and HHV7 (%) | ||
| No | 111 (65.7) | NA |
| Yes | 58 (34.3) | NA |
| Acute T2 Signal | ||
| No | 140 (88.6) | 102 (100.00) |
| Yes | 18 (11.4) | 0 (0.00) |
| Baseline EEG findings (%) | ||
| Any abnormality | 108(54.3) | NA |
| Epileptiform abnormality | 91(45.7) | NA |
NA- Not applicable