Table 3.
Quantitative analysis of healthy eyes and uveitic eyes for all groups combined.
| OCTA Layer | OCTA Variable | Healthy | Uveitis | β (95% CI) | P value |
|---|---|---|---|---|---|
| SRL | SD* | 0.097 ± 0.008 | 0.089 ±0.014 | -0.008 (-0.011, -0.006) | < 0.001 |
| VD* | 0.426 ± 0.019 | 0.378 ± 0.041 | -0.034 (-0.043, -0.024) | < 0.001 | |
| FD* | 1.713 ± 0.017 | 1.698 ± 0.032 | -0.016 (-0.022, -0.011) | < 0.001 | |
| VDI | 4.401 ± 0.342 | 4.285 ± 0.440 | 0.022 (-0.031, 0.075) | 0.56 | |
|
| |||||
| DRL | SD* | 0.102 ± 0.007 | 0.101 ± 0.009 | -0.003 (-0.005, -0.001) | 0.004 |
| VD* | 0.425 ± 0.017 | 0.412 ± 0.029 | -0.004 (0.008, 0.001) | 0.007 | |
| FD | 1.723 ± 0.016 | 1.724 ± 0.022 | -0.003 (-0.007, 0.001) | 0.05 | |
| VDI | 4.174 ± 0.316 | 4.099 ± 0.428 | 0.060 (0.005, 0.114) | 0.19 | |
|
| |||||
| NS-RL | SD* | 0.102 ± 0.008 | 0.095 ± 0.016 | -0.008 (-0.011, -0.005) | < 0.001 |
| VD* | 0.432 ± 0.020 | 0.387 ± 0.043 | -0.032 (-0.045, -0.020) | < 0.001 | |
| FD* | 1.720 ± 0.016 | 1.707 ± 0.034 | -0.017 (-0.023, -0.010) | < 0.001 | |
| VDI | 4.231 ± 0.305 | 4.119 ± 0.426 | 0.021 (-0.019, 0.061) | 0.25 | |
OCTA = optical coherence tomography angiography; SRL = superficial retinal layer; DRL = deep retinal layer; NS-RL = non-segmented retinal layer; SD = skeleton density; VD = vessel density; FD = fractal dimension; VDI = vessel diameter index.
The mean and standard deviation are reported for each set of scans (healthy or uveitis) of all group data combined within each retinal layer (Supplemental Material at AJO.com). The beta (β) represents the change in OCTA measurement value per unit increase as one transitions from healthy eyes to uveitic eyes. The 95% confidence intervals (CI) and P values for each comparison are also shown for each row of paired comparisons. Parametric analyses were used to estimate β and confidence intervals. Due to concerns of small sample size, nonparametric analysis was performed to evaluate the statistical significance of comparisons. Asterisks indicate metrics with significant differences between healthy and uveitic eyes.