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. Author manuscript; available in PMC: 2017 Dec 1.
Published in final edited form as: Hepatology. 2016 Oct 5;64(6):1951–1968. doi: 10.1002/hep.28766

Figure 4. Co-exposure with HCV and HIV induces NFκB responsive genes in LX2 cells and Huh7.5.1 cells following mock treatment, HCV exposure, HIV exposure and HIV/HCV co-exposure for 72 hours.

Figure 4

Induction of NFκB responsive genes were as measured by (A) percentage of GFP-positive cells by flow cytometry; (B) geoMFI of GFP-positive cells by flow cytometry; and (C) phosphorylated RelA. The upper panels in part C shows representative western blots of the protein levels of phosphorylated RelA, total RelA, and β Actin. The lower panel of part C depicts densitometry quantification of the ratio of P-RelA to total RelA after exposure to HCV and/or HIV for 72 hours.

* P<0.05

HCV = hepatitis C virus; HIV = human immunodeficiency virus; GFP = green fluorescence protein; geoMFI = geometric fluorescence intensity; P-RelA = phosphorylated RelA