Table 1. Subject's characteristics and subjective ratingsa on appetite and stress on arrival, and 25 min after food intake (mean±s.d.) of the severely obese and normal-weight females.
|
Severely obese (n=17) |
Normal-weight (n=12) |
Test statistic (t) | P-value | |||
|---|---|---|---|---|---|---|
| Mean | s.d. | Mean | s.d. | |||
| Body weight (kg) | 119b | 17.5 | 64b | 8.8 | −10.0 | <0.0001 |
| Body mass index (kg m−2) | 43.2b | 4.8 | 22.7b | 1.8 | −14.1 | <0.0001 |
| Age | 39 | 11.0 | 36 | 12.3 | −0.65 | 0.52 |
| Hours of sleep night preceding tests | 7.0 | 1.1 | 7.1 | 0.67 | 0.23 | 0.82 |
| Fasting plasma glucose (mmol l−1)c | 5.42b | 0.54 | 4.85b | 0.53 | −2.66 | 0.01 |
| Fasting insulin (μU ml−1)c | 20.8b | 12.9 | 5.38b | 1.69 | −4.41 | 0.001 |
| Increase in plasma glucose (mmol l−1) | 1.35 | 0.49 | 1.01 | 1.14 | −0.95 | 0.35 |
| Increase in insulin (μU ml−1) | 156.1b | 85.7 | 55.7b | 33.6 | −3.63 | 0.02 |
| Subjective ratings on arrival | ||||||
| Hunger (mm) | 58 | 18 | 54 | 20 | 1.17 | 0.60 |
| Fullness (mm) | 20 | 18 | 17 | 18 | −2.05 | 0.68 |
| Stress (mm) | 18 | 17 | 18 | 21 | 2.04 | 0.91 |
| Tiredness (mm) | 54 | 25 | 39 | 20 | −1.75 | 0.10 |
| Change in subjective ratings | ||||||
| Hunger (mm) | −21 | 24 | −8 | 18 | −1.63 | 0.12 |
| Fullness (mm) | 27 | 24 | 14 | 24 | 1.49 | 0.15 |
| Stress (mm) | −10b | 12 | +3b (increase) | 17 | −2.33 | 0.03 |
| Tiredness (mm) | −20 | 24 | −17 | 23 | −0.037 | 0.72 |
Ratings were obtained using a 100-mm visual analog scale.
Difference between obese and normal-weight participants (P<0.05).
Problems with the blood sampling procedures in the severe obese participants resulted in missing values for fasting glucose and insulin for three obese individuals (data fasting blood parameters presented for n=14), and we were not able to calculate increases in glucose and insulin concentrations for five obese individuals (data increase in blood parameters presented for n=12).