Table 2. Detailed information on clusters that show differences in the fractional amplitude of low-frequency fluctuations (fALFF) between severely obese and normal-weight individuals.
| Brain regions included in cluster (BA; nearest GM within 3 mm) | Hemisphere | Cluster sizea |
MNI |
Test statistic | ||
|---|---|---|---|---|---|---|
| x | y | z | ||||
| Interaction weight status × time: cluster with highest f | ||||||
| NS | ||||||
| Main effect BMI | ||||||
| Putamen/claustrum | R | 1641 | 30 | −19 | 13 | f=71.28 |
| Claustrum | R | 33 | 2 | 7 | f=52.21 | |
| Putamen | R | 33 | −13 | 1 | f=50.64 | |
| Putamen/claustrum | L | 513 | −24 | 2 | 19 | f=44.92 |
| Claustrum/insula | L | −30 | 17 | 4 | f=39.98 | |
| Claustrum | L | −36 | −4 | 4 | f=37.94 | |
| Postcentral gyrus/ inferior parietal lobule (BA40) | L | 49 | −54 | −28 | 22 | f=38.19 |
| Obese>normal weight after food intake | ||||||
| Putamen/claustrum | R | 2062 | 30 | −19 | 13 | t=8.44 |
| Claustrum | R | 33 | 2 | 7 | t=7.23 | |
| Putamen | R | 33 | −13 | 1 | t=7.12 | |
| Putamen/ claustrum | L | 771 | −24 | 2 | 19 | t=6.70 |
| Claustrum/insula | L | −30 | 17 | 4 | t=6.32 | |
| Claustrum | L | −36 | −4 | 4 | t=6.16 | |
| Postcentral gyrus/ inferior parietal lobule (BA40) | L | 62 | −54 | −28 | 22 | t=6.18 |
Abbreviations: BA, brodmann area; BMI, body mass index; MNI, Monteal Neurological Institute; NS, not significant; R, right; L, left.
MNI coordinates of primary peak locations; x=sagittal plane, y=coronal plane and z=axial plane.
The contrast ‘normal weight>obese after food intake' did not show significant differences in activity.
a
To identify significant clusters, we applied a cluster size threshold of 23 voxels determined by Monte Carlo simulations.