Table 3. Association between a first-degree FHD and the serum A-FABP levels.
A-FABP |
Men |
Premenopausal women |
Postmenopausal women |
||||||
---|---|---|---|---|---|---|---|---|---|
OR | 95% CI | P | OR | 95% CI | P | OR | 95% CI | P | |
Unadjusted | 1.184 | 1.075–1.303 | 0.001 | 1.128 | 1.052–1.209 | 0.001 | 1.155 | 1.072–1.244 | <0.001 |
Adjusted for BMI | 1.159 | 1.043–1.288 | 0.006 | 1.113 | 1.030–1.203 | 0.007 | 1.138 | 1.050–1.232 | 0.002 |
Adjusted for VFA | 1.147 | 1.034–1.273 | 0.010 | 1.097 | 1.019–1.182 | 0.014 | 1.135 | 1.048–1.230 | 0.002 |
Adjusted for SFA | 1.165 | 1.050–1.292 | 0.004 | 1.115 | 1.036–1.200 | 0.004 | 1.151 | 1.066–1.243 | <0.001 |
Adjusted for HOMA-IR | 1.122 | 1.012–1.243 | 0.029 | 1.116 | 1.039–1.199 | 0.003 | 1.134 | 1.049–1.226 | 0.002 |
Full model | 1.134 | 1.013–1.270 | 0.029 | 1.092 | 1.006–1.185 | 0.036 | 1.125 | 1.032–1.227 | 0.008 |
Abbreviations: A-FABP, adipokine adipocyte fatty acid binding protein; BMI, body mass index; FHD, family history of diabetes; HOMA-IR, homeostasis model assessment-insulin resistance; SFA, subcutaneous fat area; VFA, visceral fat area.
Full model included age, BMI, W, VFA, SFA, SBP, DBP, HbA1c, HOMA-IR, HOMA-β, TG, HDL-c, LDL-c and CRP.