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. 2016 Nov 18;4:122. doi: 10.1186/s40478-016-0393-5

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Cytoplasmic Matrin 3 re-localization and gliosis in ventral horn of the spinal cord in phenotypic Tg mice. a Matrin 3 immunohistochemistry shows cytoplasmic redistribution in the Tg (Fo. 1579) ventral horn compared to b NT mice. c Iba-1 immunohistochemistry shows microgliosis in Tg (Fo. 1579) mice compared to d NT mice. e GFAP immunohistochemistry shows increase staining indicative of astrocytosis in Tg (Fo. 1579) mice compared to f NT mice. g Neuron with cytoplasmic re-localization of Matrin 3 in the ventral horn of the spinal cord, surrounded by glia, as indicated by the arrow, from phenotypic founder 1576. Scale bars measure 25 μm