Table 2.
Comparison of OAB/incontinence, anxiety and other psychosocial measures between OAB with anxiety versus OAB without anxiety (adjusted for age and sex)
| OAB with anxiety (HADS-A ≥8) | OAB without anxiety (HADS-A <8) | p-value (adjusted for age and sex) | |
|---|---|---|---|
| Demographics: | |||
| No. of subjects* | 24 | 26 | |
| Age (mean ± SD) | 54.5 ± 11.1 | 53.1 ± 13.1 | 0.85 |
| Sex (% females) | 70.8% | 73.1% | 0.86 |
| HADS-A scores | 11.3 ± 2.9 | 3.9 ± 2.3 | <0.001 |
| Urinary questionnaires: (mean ± SD) | |||
| ICIQ-UI (urinary incontinence, 0–21) | 14.3 ± 4.6 | 10.3 ± 4.2 | 0.002 |
| ICIQ-OAB (overactive bladder, 0–16) | 10.3 ± 2.8 | 8.5 ± 2.3 | 0.011 |
| OAB-q symptom bother subscale (6–36) | 21.6 ± 6.1 | 17.1 ± 5.8 | 0.007 |
| OAB-q quality of life subscale (13–78) | 36.9 ± 17.7 | 22.6 ± 11.9 | 0.004 |
| UDI-6 (urogenital distress inventory, 0–24) | 15.3 ± 5.9 | 10.1 ± 4.3 | 0.001 |
| IIQ-7 (incontinence impact questionnaire, 0–28) | 12.7 ± 9 | 5.3 ± 5.6 | 0.001 |
| Other psychosocial measures: (mean ± SD) | |||
| Depression (HADS-D) | 8.0 ± 3.5 | 2.5 ± 3.5 | <0.001 |
| Psychological stress level (PSS) | 23.1 ± 6.3 | 11.8 ± 5.5 | <0.001 |
| Somatic symptom burden (PSPS- Q) | 24.5 ± 11.3 | 11.0 ± 9.6 | <0.001 |
| Exposure to childhood sexual trauma (CTES) | 37.5% | 23.1% | 0.162 |
| Sleep (PROMIS-8b) | 58.2 ± 10.1 | 50.7± 9.6 | 0.012 |
| Fatigue (PROMIS-7a) | 59.2 ± 8.8 | 50.5 ± 8.6 | 0.001 |