Table 3.
Bivariate and multivariable odds ratios (OR) and 95% confidence intervals (CI) for any ART non-adherence in the prior 30 days, BREATH Study, Mbarara, Uganda (n=134 participants, n=253 observations).
| Bivariate | Multivariable | ||||
|---|---|---|---|---|---|
| OR (95% CI) | Wald X2 (p-value) |
OR (95% CI) | Wald X2 (p-value) |
||
| Interactive toxicity items, each visit | |||||
| “I think that people
who take alcohol should stop taking their medications because they should not mix them” (belief) |
0.79 (0.38) | 1.72 (0.19) | |||
| False | 1.00 | 1.00 | |||
| True | 0.76 (0.42, 1.39) | 0.63 (0.32, 1.26) | |||
| “I occasionally stop
taking any medications I am on if I think I will be drinking alcohol” (behavior) |
2.06 (0.15) | 3.55 (0.06) | |||
| False | 1.00 | 1.00 | |||
| True | 1.60 (0.84, 3.02) | 2.06 (0.97, 4.36) | |||
| Baseline demographics | |||||
| Sex | 2.10 (0.15) | ||||
| Female | 1.00 | - | |||
| Male | 0.64 (0.35, 1.17) | - | |||
| Marital status | 5.75 (0.02) | 5.62 (0.02) | |||
| Married | 1.00 | 1.00 | |||
| Not married | 2.04 (1.14, 3.66) | 2.04 (1.13, 3.69) | |||
| Age (years) | 1.12 (0.57) | ||||
| 18–25 | 1.00 | - | |||
| 26–35 | 0.86 (0.42, 1.76) | - | |||
| >35 | 0.67 (0.31, 1.43) | - | |||
| Education | 1.37 (0.24) | ||||
| Primary education or less | 1.00 | - | |||
| More than a primary education | 0.69 (0.38, 1.28) | - | |||
| Religion | 0.98 (0.61) | ||||
| Protestant | 1.00 | - | |||
| Catholic | 1.32 (0.71, 2.43) | - | |||
| Other | 0.73 (0.13, 4.27) | - | |||
| Household assets | 0.59 (0.74) | ||||
| Low | 1.00 | - | |||
| Middle | 0.97 (0.51, 1.82) | - | |||
| Rich | 0.71 (0.29, 1.76) | - | |||
| Household Food Security | 0.16 (0.92) | ||||
| Food secure | 1.00 | - | |||
| Mildly/moderately food insecure | 0.90 (0.46, 1.77) | - | |||
| Severely food insecure | 1.03 (0.48, 2.19) | - | |||
| Low social support? | 0.40 (0.53) | ||||
| No | 1.00 | - | |||
| Yes | 1.28 (0.59, 2.78) | - | |||
| Time to clinic visit (minutes) | 4.33 (0.23) | ||||
| 0–20 | 1.00 | - | |||
| 21–40 | 0.48 (0.23, 1.04) | - | |||
| 41–60 | 0.60 (0.27, 1.32) | - | |||
| >60 | 0.90 (0.42, 1.97) | - | |||
| Study arm | 0.57 (0.45) | ||||
| Main cohort arm | 1.00 | - | |||
| Minimally assessed arm | 1.31 (0.65, 2.64) | - | |||
| At each visit | |||||
| General health status, past 3 months | 1.34 (0.25) | ||||
| Good/very good/excellent | 1.00 | - | |||
| Fair/poor | 1.49 (0.76, 2.94) | - | |||
| Affective symptoms of
depression, past 3 months? |
2.33 (0.13) | ||||
| No | 1.00 | - | |||
| Yes | 2.13 (0.81, 5.63) | - | |||
| Unhealthy alcohol use, past 3
months (self-report hazardous or PEth ≥ 50) |
5.31 (0.02) | 3.72 (0.05) | |||
| No | 1.00 | 1.00 | |||
| Yes | 1.92 (1.10, 3.33) | 1.75 (0.99, 3.08) | |||
| Months on ART at this visit | 1.00 (0.93, 1.08) | 0.00 (0.98) | - | ||
| Number of clinic visits, past 3 months | 0.97 (0.77, 1.22) | 0.08 (0.78) | - | ||