Table 2.
Genotype frequencies of VDR polymorphisms in 7 studies included in this systematic review and meta-analysis.
| Author | Genotype frequencies | Allele frequencies | P-HWE | ||
|---|---|---|---|---|---|
| Case | Control | Case | Control | ||
| FokI | FF/Ff/ff | FF/Ff/ff | F/f | F/f | |
| Zhong et al. | 11/53/30 | 35/61/14 | 75/113 | 131/89 | 0.113 |
| Hou et al. | 10/40/112 | 12/34/46 | 60/264 | 58/126 | 0.167 |
| Wu et al. | 6/37/19 | 21/35/12 | 49/75 | 77/59 | 0.694 |
| Bućan et al. | 6/9/4 | 7/15/6 | 21/17 | 29/27 | 0.700 |
| Cyganek et al. | 20/45/20 | 51/93/38 | 85/85 | 195/169 | 0.713 |
| Taverna et al. | 38/65/23 | 57/56/15 | 141/111 | 170/86 | 0.826 |
|
| |||||
| BsmI | Bb/Bb/bb | Bb/Bb/bb | B/b | B/b | |
| Zhong et al. | 5/27/62 | 6/27/77 | 37/151 | 39/181 | 0.096 |
| Bućan et al. | 2/10/7 | 5/16/7 | 14/24 | 26/30 | 0.431 |
| Cyganek et al. | 10/37/38 | 21/84/77 | 57/113 | 126/238 | 0.791 |
|
| |||||
| TaqI | TT/Tt/tt | TT/Tt/tt | T/t | T/t | |
| Bućan et al. | 7/8/4 | 11/12/5 | 22/16 | 34/22 | 0.591 |
| Cyganek et al. | 40/38/7 | 82/81/19 | 118/52 | 245/119 | 0.879 |
| Taverna et al. | 27/58/16 | 42/44/13 | 112/90 | 128/70 | 0.783 |
|
| |||||
| ApaI | AA/Aa/aa | AA/Aa/aa | A/a | A/a | |
| Zhong et al. | 27/54/13 | 34/60/16 | 108/80 | 128/92 | 0.205 |
| Cyganek et al. | 17/39/29 | 39/100/43 | 73/97 | 278/283 | 0.178 |
MAF: minor allele frequency.
HWE: Hardy-Weinberg equilibrium.