Table 4.
Effects of endogenous omega-3 fatty acids on oxidative stress parameters in the liver.
| Parameters | WT | WT/CCl4 | Fat-1/CCl4 |
|---|---|---|---|
| MDA (nmol/mg protein) | 2.52 ± 0.34 | 4.73 ± 0.52## | 3.99 ± 0.54∗∗ |
| SOD (U/mg protein) | 303.8 ± 33.8 | 214.3 ± 32.8# | 261.8 ± 44.2∗∗ |
| CAT (U/mg protein) | 13.5 ± 1.9 | 7.52 ± 2.26# | 9.97 ± 2.10∗ |
| GSH-Px (U/mg protein) | 975.6 ± 317.2 | 565.4 ± 199.1## | 770.1 ± 283.4∗∗ |
| GR (U/g protein) | 10.6 ± 1.7 | 6.22 ± 1.77## | 7.92 ± 1.72∗ |
| GSH (mg/g protein) | 11.6 ± 1.8 | 7.96 ± 0.89## | 9.27 ± 1.93∗∗ |
| GSSG (mg/g protein) | 1.26 ± 0.36 | 2.29 ± 0.56## | 1.72 ± 0.40∗ |
| GSH/GSSG (fold) | 9.72 ± 2.27 | 3.62 ± 0.89## | 5.46 ± 0.94∗∗ |
Data are expressed as mean ± SD (n = 10). # p < 0.05 and ## p < 0.01 versus WT group; ∗ p < 0.05 and ∗∗ p < 0.01 versus WT/CCl4 group.