Fig. 3.

Clinical manifestation grading and weight loss of the recipients following SBTx. a Clinical manifestation scores were much higher in the allogeneic control (Allo) group compared with the BMMSC treatment group. HO-1 transduction markedly reduced the score, especially on days 7 and 10. b The majority of the animals suffered weight loss following SBTx. BMMSC treatment, especially when transduced with Ad/HO-1, significantly improved or even reversed this effect compared with the allogeneic control group. The least amount of weight loss occurred in the Ad/HO-1/BMMSC group, especially on days 7 and 10. Data expressed as mean ± SD (*P < 0.05 compared with allogeneic controls; ^# P < 0.05 compared with BMMSC controls; ^$ P < 0.05 compared with Ad/BMMSC controls). Ad adenoviral vector, BMMSC bone marrow mesenchymal stem cell, HO-1 heme oxygenase-1, SBTx small bowel transplantation