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PKCδ: Functionally important motifs for apoptosis. Y64 and Y155 are known to be required for nuclear import in response to apoptotic signals. Other tyrosine residues known to be of functional importance are also shown. The nuclear localization signal (NLS) in the V5 region is highlighted in blue. Caspase cleavage in the hinge region releases a constitutively active, nuclear-targeted form of PKCδ. See text for details.
