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Changes in Immunohistochemical staining pre- and post-treatment
| Biomarker | Increase | No Change | Decrease | P-value |
|---|---|---|---|---|
| Phospho-ACC (activation of AMPK) |
2 (10%) | 13 (65%) | 5 (25%) | 0.979 |
| Phospho-S6rp | 1 (5%) | 5 (25%) | 14 (70%) | 0.057 |
| MAPK | 1 (5.6%) | 2 (11.1%) | 15 (83.3%) | 0.004 |
| Phospho-AKT | 1 (5%) | 1 (5%) | 18 (90%) | 0.002 |
| Ki67 (cell proliferation) | 1 (5%) | 13 (65%) | 6 (30%) | 0.942 |
| Caspase 3 (apoptosis) | 3 (15%) | 12 (60%) | 5 (25%) | 0.979 |
