Table 1.
Demographic and clinical data.
| Aβ(+) (n = 30) | Aβ(−) (n = 20) | p-Value (Aβ+ vs. Aβ−) | |
|---|---|---|---|
| Age, years | 63.77 (6.99) | 59.85 (7.29) | 0.062a |
| Women/men, n | 19/11 | 10/10 | 0.349b |
| MMSE | 27.70 (1.34) | 28.15 (1.50) | 0.254c |
| SCD/MCI diagnoses, n (%) | 3 (10.0)/27 (90.0) | 4 (20.0)/16 (80.0) | 0.281b |
| CSF Aβ42, ng/L | 521.07 (133.23) | 1036.80 (120.82) | <0.001a,* |
| WMH volume, mm3 | 5542.76 (7321.89) | 3345.38 (5063.31) | 0.291a,d |
Values are given in mean (SD) unless otherwise indicated.
aCalculated using independent-samples T-test.
bCalculated using Pearson chi-square test.
cCalculated using Mann–Whitney U test.
dp-Value for log transformed WMH volume adjusted for age.
*Significant difference between the two groups.
CSF, cerebrospinal fluid; Aβ, amyloid β-peptide; WMH, white matter hyperintensity; MMSE, mini-mental state examination; MCI, mild cognitive impairment; SCD, subjective cognitive decline.