Table 2. Adverse events.
|
Vector dose level (vp) |
||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DL-1 (1 × 1010) | DL-2 (1 × 1011) |
DL-3 (1 × 1012) |
DL-4 (3 × 1012) | |||||||||||||||
|
Patient no. |
||||||||||||||||||
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | |
| Fever | — | — | — | — | Grade 1 | Grade 1 | Grade 2 | Grade 1 | Grade 2 | — | Grade 1 | Grade 2 | Grade 2 | Grade 2 | Grade 2 | Grade 2 | Grade 2 | Grade 2 |
| TA elevation | — | — | — | — | — | — | — | Grade 1 | — | Grade 1 | — | — | Grade 2 | — | — | — | Grade 2 | — |
| Others (possibly related) | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
Abbreviations: ALT, alanine transaminase; AST, aspartate transaminase; DL, dose level; TA, transaminases (alanine transaminase and aspartate transaminase); vp, viral particles.