Table 3. Changes in serum-neutralizing antibody titer against adenovirus.
| Day 0 | Day 14 | Day 28 | Day 56 | Day 84 | |
|---|---|---|---|---|---|
| DL-1 | |||||
| 1 | <4 | <4 | 32 | 8 | 32 |
| 2 | 16 | 16 | 8 | 4 | 16 |
| 3 | 16 | 512 | 512 | 1024 | 1024 |
| DL-2 | |||||
| 4 | 4 | 16 | 64 | 128 | 128 |
| 5 | 16 | 64 | 128 | 32 | 128 |
| 6 | 32 | 512 | 256 | 1024 | 512 |
| DL-3 | |||||
| 7 | <4 | 64 | 128 | 128 | 32 |
| 8 | 128 | 256 | 512 | 256 | 256 |
| 9 | 32 | 256 | 256 | 256 | 512 |
| 10 | 4 | 4 | 4 | 8 | 16 |
| 11 | 64 | 32 | 32 | 32 | 64 |
| 12 | <4 | 16 | 32 | 64 | 64 |
| DL-4 | |||||
| 13 | <4 | 128 | 128 | 128 | 128 |
| 14 | 4 | 32 | 64 | 32 | 64 |
| 15 | 16 | 32 | 128 | 128 | 64 |
| 16 | 16 | 32 | 64 | 1024 | 512 |
| 17 | 4 | 64 | 128 | 128 | 128 |
| 18 | 16 | 128 | 64 | 128 | 128 |
Abbreviation: DL, dose level.