Table 3. Changes in serum-neutralizing antibody titer against adenovirus.
Day 0 | Day 14 | Day 28 | Day 56 | Day 84 | |
---|---|---|---|---|---|
DL-1 | |||||
1 | <4 | <4 | 32 | 8 | 32 |
2 | 16 | 16 | 8 | 4 | 16 |
3 | 16 | 512 | 512 | 1024 | 1024 |
DL-2 | |||||
4 | 4 | 16 | 64 | 128 | 128 |
5 | 16 | 64 | 128 | 32 | 128 |
6 | 32 | 512 | 256 | 1024 | 512 |
DL-3 | |||||
7 | <4 | 64 | 128 | 128 | 32 |
8 | 128 | 256 | 512 | 256 | 256 |
9 | 32 | 256 | 256 | 256 | 512 |
10 | 4 | 4 | 4 | 8 | 16 |
11 | 64 | 32 | 32 | 32 | 64 |
12 | <4 | 16 | 32 | 64 | 64 |
DL-4 | |||||
13 | <4 | 128 | 128 | 128 | 128 |
14 | 4 | 32 | 64 | 32 | 64 |
15 | 16 | 32 | 128 | 128 | 64 |
16 | 16 | 32 | 64 | 1024 | 512 |
17 | 4 | 64 | 128 | 128 | 128 |
18 | 16 | 128 | 64 | 128 | 128 |
Abbreviation: DL, dose level.