Table 2.
Associations between baseline skin cancer risk factors and subsequent cutaneous squamous cell carcinoma (SCC).
| Variable | No subsequent SCC (n = 59) n (%) |
Subsequent SCC (n = 91) n (%) |
P value for Chi Square test |
|---|---|---|---|
| Age [mean (STD)] | 62.9 (12.4) | 65.4 (8.4) | 0.161 |
| Gender | |||
| Female | 24 (40.7) | 26 (28.6) | 0.12 |
| Male | 35 (59.3) | 65 (71.4) | |
| History of blistering sunburn prior to index SCC diagnosis | |||
| No | 15 (28.3) | 14 (18.2) | |
| Yes | 38 (71.7) | 63 (81.8) | 0.17 |
| Tanning ability | |||
| No | 11 (21.6) | 12 (15.0) | |
| Yes | 40 (78.4) | 68 (85.0) | 0.33 |
| Job in sun for more than 3 months at any time in life prior to the index SCC diagnosis | |||
| No | 31 (59.6) | 39 (48.7) | 0.22 |
| Yes | 21 (40.4) | 41 (51.2) | |
| Smoking | |||
| Never | 17 (32.1) | 23 (29.9) | |
| Ever | 36 (67.9) | 54 (70.1) | 0.79 |
| Alcohol | |||
| Never drinker | 12 (23.5) | 15 (18.7) | 0.51 |
| 1 or more drinks in past 1 year | 39 (76.5) | 65 (81.2) | |
| History of SCC prior to index SCC diagnosis | |||
| No | 7 (15.6) | 1 (1.5) | |
| Yes | 38 (84.4) | 65 (98.5) | 0.0072 |
| History of BCC prior to index SCC diagnosis | |||
| No | 7 (21.2) | 2 (3.6) | |
| Yes | 26 (78.8) | 53 (96.4) | 0.012 |
| History of SCC and BCC prior to index SCC diagnosis | |||
| No | 7 (21.9) | 1 (2.0) | 0.0052 |
| Yes | 25 (78.1) | 49 (98.0) | |
| Number of HPV types in index SCC tumors | |||
| 0 | 23 (42.6) | 22 (28.6) | 0.17 |
| 1 | 12 (22.2) | 14 (18.2) | |
| 2–5 | 17 (31.5) | 33 (42.9) | |
| >5 | 2 (3.7) | 8 (10.4) |
1Student's t-test. 2Fisher's exact test.