Table 3.
MELK and IL11RA gene copy number and clinicopathological features of 68 gastric cancer patients
|
MELK |
IL11RA |
|||||
| 2 copies (n = 38) | ≥ 3 copies (n = 30) | P value | 2 copies (n = 55) | ≥ 3 copies (n = 13) | P value | |
| Age (yr) (mean ± SD) | ||||||
| > 50 (64.5 ± 6.9) | 23 | 25 | 0.0748 | 39 | 9 | 0.7461 |
| ≤ 50 (42.5 ± 5.2) | 15 | 5 | 16 | 4 | ||
| Gender | ||||||
| Male | 23 | 21 | 0.5781 | 34 | 9 | 0.7544 |
| Female | 15 | 9 | 21 | 4 | ||
| Histopathology | ||||||
| Intestinal | 23 | 20 | 0.7886 | 32 | 11 | 0.1110 |
| Diffuse | 15 | 10 | 23 | 2 | ||
| Depth of tumor invasion | ||||||
| pT1-pT2 | 10 | 11 | 0.5137 | 18 | 3 | 0.4076 |
| pT3-pT4 | 28 | 19 | 36 | 10 | ||
| Lymph node metastasis | ||||||
| Absent | 10 | 7 | 1.0000 | 11 | 6 | 0.1091 |
| Present | 28 | 23 | 44 | 7 | ||
| Stage | ||||||
| I-II | 25 | 17 | 0.6049 | 33 | 9 | 0.7525 |
| III-IV | 13 | 13 | 22 | 4 | ||