Table 7.

Selected High-Affinity Binding (IC50 < 50 nM) Fifteen-mer Human MHC Class II Epitopes

Serial No.	Allergen	GI number	Start	End	Epitope
1	Asp f1	166486	1	15	MVAIKNLFLLAATAV
			39	53	PKTNKWEDKRLLYSQ
			40	54	KTNKWEDKRLLYSQA
			49	63	LYSQAKAESNSHHAP
			75	89	HWFTNGYDGNGKLIK
2	Asp f2	1881574	4	18	LLRLAVLLPLAAPLV
			226	240	AFEYFALEAYAFDIA
			15	29	APLVATLPTSPVPIA
			204	218	DGYDEVIALAKSNGT
3	Asp f4	3005839	5	20	DTVYATINGVLVSWI
			37	51	TPVSNAVAAAAAAST
			40	54	GELCSIISHGLSKVI
4	Asp f5	3776613	1	15	MRGLLLAGALALPAS
			179	193	EKESYVFKGVSGTVS
			64	78	PQSYVEVATQHVKMI
			576	590	CNPNFVQARDAILDA
			505	519	TNPLTYTSVNSLNAV
			308	322	LNNYRPSSSSLSFKY
			305	319	PSYLNNYRPSSSSLS
5	Asp f7	2879888	15	28	VGQLTYYDTATSASA
6	Asp f9	2879890	9	23	ADMYFKYTAAALAAV
			18	32	AALAAVLPLCSAQTW
			238	252	YSAGPYTMYVKSVRI
			274	288	KFDGSVDISSSSSVT
			104	118	AEVVMKAAPGTGVVS
7	Asp f15	3005841	68	82	GSVPGFARIGGAPTI
			6	20	PISLISLFVSSALAA
			1	15	MKFTTPISLISLFVS
8	Asp f16	3643813	102	116	GGTVYEDLKAQYTAA
			43	57	SEKLVSTINSGVDTV
			100	114	NAGGTVYEDLKAQYT
			114	128	TAADSLAKAISAKVP
			15	29	SDISAQTSALASAVS
9	Asp f17	2980819	1	15	MYFKYTAAALAAVLP
			260	274	AEHQVRRLRRYSSSS
			196	210	PQTPMRLRLAAGPAA
			93	108	AEVVMKAAPGTGVVS
			340	354	LRLRLWLWLYSSTGS
10	Asp f34	133920236	1	15	MQIKSFVLAASAAAT
			39	53	AVQYQPFSAAKSSIF
			48	62	AKSSIFAGLNSQNAS
			75	89	IQDGSLYLYAASATP
			25	39	TNKYFGIVAIHSGSA