FIG 1.

Modulation of TLR2 mRNA expression in tissues after injection of leptospires. TLR2 mRNA levels in kidneys, livers, and lungs from BALB/c mice and hamsters were quantified by RT-qPCR at a series of time points. The results were normalized to the expression level of the housekeeping gene GAPDH. Bars show the levels of TLR2 (means ± standard deviations) in tissues of mice and hamsters at each time point (n = 3). The levels of TLR2 in different tissues from three healthy individuals at 0 h were given a value of 1.0. Different mRNA expression levels between the infected group and the healthy group (0 h) were compared by one-way ANOVA. *, P < 0.05.