FIG 3.
Colonization of Sigirr−/− mice by wild-type C. jejuni and mutant and complemented strains as CFU per gram recovered from the cecum of Sigirr−/− mice colonized by wild-type C. jejuni 81-176 and Δpgp1, Δpgp2, and Δ1228 mutant strains and the Δpgp1c, Δpgp2c, and Δ1228c complemented strains, all at 7 days postinfection. Most colonization levels ranged between 108 and 109 CFU/g, with Δpgp1 and Δpgp2 mutants having on average a slightly reduced pathogen burden per gram of tissue/luminal contents compared with the other strains, although this was not statistically significant. Statistical significance was determined using a Mann-Whitney test (P < 0.05). No strains met this threshold.