Table 1.
Progression of infectiousness in pigs inoculated with FMDV via intra-oropharyngeal (IOP) route.
| Contact group | Exposure timea (hpi) | Donor pig characteristics during exposure |
Infected contact pigs (infected/not infected) | Infectious phase of donors | |||
|---|---|---|---|---|---|---|---|
| Viremia | Clinical FMD | FMDV RNA in OPFb |
|||||
| Start exposure | End exposure | ||||||
| 1 | 8–16 | No | No | 5.22 | 6.45 | 0/5 | Latent |
| 2 | 16–24 | No | No | 6.45 | 6.51 | 0/5 | Latent |
| 3 | 24–32 | Yes | No | 6.51 | 7.22 | 5/0 | Infectious (incubation) |
| 4 | 32–40 | Yes | No | 7.22 | 8.31 | 5/0 | Infectious (incubation) |
| 5 | 40–48 | Yes | Yes | 8.31 | 8.10 | 5/0 | Infectious (clinical) |
| 6 | 48–52 | Yes | Yes | 8.10 | 8.10 | 5/0 | Infectious (clinical) |
| 7 | 52–64 | Yes | Yes | 8.10 | 9.00 | 5/0 | Infectious (clinical) |
aExpressed as hours post-infection of donors.
bExpressed as log10 GCN/ml.