Table 2. . Differences in mean NR3C1 levels by child abuse among 295 Black Women's Health Study participants (2005).
Severity and type of abuse | Number of women (%) |
NR3C1 % |
Unadjusted β (95% CI)† | Age-adjusted β (95% CI) | Multivariable-adjusted β (95% CI)† | |
---|---|---|---|---|---|---|
Mean | Std Err | |||||
No child abuse |
142 (48.1) |
51.8 |
0.37 |
Referent (0.00) |
Referent (0.00) |
Referent (0.00) |
Any child abuse |
153 (51.9) |
52.7 |
0.36 |
0.88 (-0.14, 1.89) |
0.93 (-0.10, 1.96) |
1.02 (-0.02, 2.06) |
Physical abuse frequency
| ||||||
Low |
51 (18.4) |
51.9 |
0.63 |
0.22 (-1.29, 1.73) |
0.30 (-1.21, 1.81) |
0.36 (-1.16, 1.88) |
Intermediate |
32 (11.6) |
52.0 |
0.79 |
0.27 (-1.51, 2.06) |
0.31 (-1.47, 2.09) |
0.60 (-1.22, 2.43) |
High |
52 (18.8) |
53.6 |
0.63 |
1.89 (0.39, 3.40) |
2.06 (0.54, 3.59) |
2.20 (0.65, 3.75) |
p-trend |
|
|
|
0.022 |
0.014 |
0.008 |
Sexual abuse frequency
| ||||||
One to three incidents |
41 (19.6) |
54.1 |
0.92 |
2.85 (0.48, 5.22) |
2.79 (0.38, 5.21) |
2.70 (0.30, 5.10) |
Four or more incidents |
26 (12.4) |
53.6 |
1.12 |
2.33 (-0.37, 5.04) |
2.29 (-0.44, 5.02) |
2.13 (-0.53, 4.89) |
p-trend |
|
|
|
0.110 |
0.126 |
0.159 |
Severity of abuse
| ||||||
Mild |
33 (10.9) |
52.0 |
0.77 |
0.21 (-1.48, 1.89) |
0.25 (-1.44, 1.94) |
0.34 (-1.37, 2.05) |
Moderate |
52 (17.1) |
52.7 |
0.62 |
0.87 (-0.54, 2.28) |
0.92 (-0.50, 2.34) |
1.02 (-0.42, 2.45) |
Severe |
58 (19.1) |
52.9 |
0.58 |
1.13 (-0.23, 2.49) |
1.20 (-0.17, 2.57) |
1.34 (-0.04, 2.73) |
Very severe |
10 (3.3) |
53.4 |
1.40 |
1.63 (-1.22, 4.49) |
1.69 (-1.17, 4.56) |
1.45 (-1.45, 4.34) |
p-trend | 0.045 | 0.037 | 0.029 |
Tests for trend include zero level of exposure (i.e., no child abuse).
No child abuse is reference group for all comparisons. All models of sexual abuse control for physical abuse, and vice versa.
†Adjusted for age at baseline (centered at median age: 43 years) and parental education (<12, 12, 13–15, ≥16 years, missing/unknown).
β: Mean difference; Std Err: Standard error.