. 2016 Nov 1;25(11):1187–1192. doi: 10.1089/jwh.2015.5657

Table 4.

Multivariate Analysis of Reported Symptom Prevalence

		Annual visit			Problem visit
Outcome	Predictor	OR	95% CI	p	OR	95% CI	p
Irregular/unpredictable periods	Case	1.43	0.80–2.56	0.227	1.38	0.74–2.57	0.316
	Postmenopause	0.62	0.37–1.03	0.066	0.22	0.12–1.40	<0.001^a
	Obese	1.65	0.99–2.75	0.056	1.25	0.71–2.22	0.437
Bleeding between periods	Case	2.07	0.92–4.64	0.078	1.84	0.78–4.34	0.166
	Postmenopause	0.13	0.06–0.29	<0.001^a	0.09	0.04–0.20	<0.001^a
	Obese	1.12	0.56–2.24	0.746	1.30	0.61–2.76	0.500
Heavy periods	Case	1.60	0.89–2.87	0.116	1.49	0.79–2.80	0.216
	Postmenopause	0.69	0.42–1.16	0.161	0.28	0.15–0.53	<0.001^a
	Obese	1.85	1.11–3.06	0.017^a	2.19	1.23–3.88	0.007^a
Prolonged periods (>7 days)	Case	3.01	1.51–6.03	0.002^a	1.75	0.88–3.51	0.112
	Postmenopause	0.28	0.14–0.53	<0.001^a	0.19	0.10–0.37	<0.001^a
	Obese	1.31	0.71–2.43	0.392	1.46	0.78–2.72	0.233
Bleeding after sex	Case	3.02	1.04–8.75	0.042^a	0.99	0.39–2.54	0.986
	Postmenopause	0.25	0.09–0.69	0.008^a	0.25	0.11–0.59	0.002^a
	Obese	0.66	0.24–1.79	0.417	1.21	0.53–2.77	0.657
Bleeding after menopause	Case	29.46	12.02–72.18	<0.001^a	5.50	2.38–12.72	<0.001^a
	Obese	1.43	0.60–3.39	0.417	1.65	0.78–3.47	0.191
Pelvic pain	Case	4.35	2.33–8.12	<0.001^a	1.94	1.05–3.57	0.034^a
	Postmenopause	0.48	0.27–0.85	0.011^a	0.48	0.27–0.85	0.013^a
	Obese	2.43	1.42–4.16	0.001^a	1.52	0.87–2.63	0.138
Pelvic pressure	Case	7.05	3.39–14.66	<0.001^a	1.48	0.81–2.70	0.204
	Postmenopause	0.58	0.28–1.20	0.139	1.03	0.57–1.86	0.916
	Obese	1.43	0.72–2.87	0.309	1.28	0.72–2.26	0.396
Urinary frequency	Case	2.32	1.29–4.19	0.005^a	1.21	0.68–2.18	0.519
	Postmenopause	2.48	1.38–4.45	0.002^a	1.35	0.78–2.37	0.285
	Obese	1.87	1.07–3.26	0.028^a	1.53	0.89–2.63	0.123
Bowel habits	Case	1.40	0.77–2.56	0.275	1.11	0.60–2.04	0.744
	Postmenopause	1.30	0.74–2.30	0.363	0.96	0.53–1.72	0.884
	Obese	1.87	1.07–3.26	0.027^a	1.76	0.99–3.12	0.052
Discharge	Case	9.41	4.68–18.92	<0.001^a	3.32	1.79–6.15	<0.001^a
	Postmenopause	0.51	0.26–1.03	0.060	0.80	0.44–1.46	0.470
	Obese	1.63	0.85–3.11	0.138	1.22	0.68–2.18	0.499
Fatigue	Case	2.28	1.28–4.08	0.005^a	1.35	0.74–2.46	0.330
	Postmenopause	0.85	0.50–1.42	0.533	0.65	0.37–1.15	0.141
	Obese	1.73	1.04–2.87	0.035^a	1.82	1.05–3.14	0.032^a

All models included terms for obesity, menstrual status, and case–control status.

^{^a}

p < 0.008 to control for multiple testing on primary objective.