Table 2.

Pharmacokinetic data showing mean serum levels (ng/ml) of buprenorphine in mice following a single subcutaneous injection of either buprenorphine HCl or buprenorphine in hydrogel.

Column 1	Column 2	Column 3	Column 4
Time	Buprenophine HCl (0.1 mg/kg)	Buprenorphine HCl in Pluronic™ gel (1.0 mg/kg)	Buprenorphine HCl in Pluronic™ gel (0.5 mg/kg)
1 h	2.89	10.83	*
4 h	1.63	6.74	10.55
8 h	8.6	20.93	9.87
12 h	1.31	8.89	*
24 h	*	16.66	0.71
48 h	*	2.01	*

^*denotes blood collection not done.