Table 1.
Number of study participants and demographic data for subjects meeting eligibility criteria.
| Demographic and Clinical Covariates | Treatment Group: Nasal Oxygen | Treatment Group: bCPAP | |
| Transitioned from Nasal | |||
| Oxygen to bCPAP | bCPAP | ||
| Number of study participants | |||
| Number of subjects completing study | 25 | 9 | 55 |
| Number of subjects meeting eligibility criteria | 25 | 9 | 53 |
| Gender | |||
| % Male | 60.0% | 44.4% | 60.4% |
| % Female | 40.0% | 55.6% | 39.6% |
| Gestational Age | |||
| Average (weeks) | 33.0 weeks | 32.0 weeks | 33.2 weeks |
| Unknown (%) | 12.0% | 0.0% | 9.4% |
| Average Birth Weight (kg) | 1.68 kg | 1.37 kg | 1.79 kg |
| Very Low Birth Weight (> = 1.0 kg–,1.5 kg) (%) | 52.0% | 41.5% | 77.8% |
| Low Birth Weight (> = 1.5 kg–<2.5 kg) (%) | 28.0% | 41.5% | 22.2% |
| Birth Weight > = 2.5 kg (%) | 20.0% | 17.0% | 0.0% |
| Location of birth | |||
| Queen Elizabeth Central Hospital (QECH) (%) | 60.0% | 55.6% | 56.6% |
| Outside QECH (%) | 32.0% | 44.4% | 32.1% |
| Unknown (%) | 8.0% | 0.0% | 11.3% |
| Singletons vs. Multiples | |||
| Singletons (%) | 52.0% | 44.5% | 73.6% |
| Multiples (%) | 44.0% | 44.4% | 26.4% |
| Unknown (%) | 4.0% | 11.1% | 0.0% |
| Received bag & mask ventilation prior to therapy? | |||
| Yes (%)* | 4.0% | 22.2% | 24.5% |
| No (%) | 88.0% | 66.7% | 54.7% |
| Unknown (%) | 8.0% | 11.1% | 20.8% |
| HIV Status | |||
| Exposed | 20.0% | 33.3% | 22.7% |
| Unexposed | 64.0% | 44.4% | 67.9% |
| Unknown | 16.0% | 22.2% | 9.4% |
| Entry vital statistics | |||
| Average entry heart rate (beats per minute (bpm)) | 144 bpm | 148 bpm | 141 bpm |
| Average entry respiratory rate (bpm) | 54 bpm | 55 bpm | 54 bpm |
| Average entry oxygen saturation (%) | 92% | 91% | 88% |
| Primary Diagnosis | |||
| RDS | 68.0% | 100.0% | 73.6% |
| Congenital Pneumonia | 4.0% | 0.0% | 18.9% |
| Acquired Pneumonia | 4.0% | 0.0% | 0.0% |
| Meconium Aspiration | 8.0% | 0.0% | 5.7% |
| Transient Tachypnea of the Newborn | 12.0% | 0.0% | 0.0% |
| Stridor | 4.0% | 0.0% | 0.0% |
| Asphyxia | 0.0% | 0.0% | 1.8% |
| Co-Morbidities | |||
| Sepsis | 28.0% | 44.4% | 41.5% |
*
Difference in group receiving nasal oxygen and bCPAP significantly different (p = 0.015).
doi:10.1371/journal.pone.0086327.t001