Differences in PCR-Adjusted and PCR-Unadjusted Treatment Success Rates at Day 63, According to Pairwise Analysis and Country.
In the estimation of the polymerase-chain-reaction (PCR)-adjusted cure rate, only recurrent infections that were shown by means of genotyping to be the same infections as those before treatment (recrudescences) were considered to be treatment failures. Conversely, for the estimation of the PCR-unadjusted cure rate, all recurrent infections were considered to be treatment failures. A positive value in the difference reflects a higher cure rate in the treatment listed first. If the difference in the cure rates was less than 5 percentage points (red lines), the treatments were considered to be therapeutically equivalent. Dashed horizontal lines indicate the 95% confidence intervals for the comparisons of treatment groups within a single country; solid horizontal lines are used for comparisons of total data from two countries.