Table 2.
Before surgery |
After surgery |
Change from baseline (95% CI) |
||||
---|---|---|---|---|---|---|
Lobectomy n=58 |
Pulmonectomy n=12 |
Lobectomy n=51 |
Pulmonectomy n=8 |
Lobectomy n=51 |
Pulmonectomy n=8 |
|
FEV1, L | 2.4±0.8 | 2.6±0.7 | 2.0±0.6 | 1.7±0.3 | −0.4 (−0.5 to −0.3) | −0.9 (−1.3 to −0.5) |
DLCO, mmol/min/kPa | 6.7±2.1 | 7.2±2.3 | 5.5±1.6 | 4.8±1.2 | −1.3 (−1.6 to −1.0) | −2.7 (−4.1 to −1.3) |
V̇O2peak, mL/kg/min | 23.4±5.5 | 26.2±6.9 | 19.5±5.4 | 17.8±6.6 | −4.3 (−5.4 to −3.3)* | −9.2 (−14.3 to −4.2)* |
VEpeak, L/min | 59.8±18.0 | 67.3±16.0 | 47.4±14.0 | 44.4±16.6 | −11.3 (−14.8 to −7.8)* | −21.6 (−32.8 to −10.3)* |
Breathing reserve, % | 35.3±14.9 | 34.8±11.0 | 41.8±13.0 | 41.0±15.3 | 5.8 (3.0 to 8.6)* | 2.5 (−12.0 to 16.9) |
SpO2peak, % | 93.4±4.1 | 90.3±6.7 | 93.3±3.3 | 92.9±3.4 | −0.6 (−0.2 to 1.5) | 0.9 (−3.3 to 1.5) |
Oxygen pulse, mL/beat | 11.8±3.5 | 13.1±3.9 | 10.0±2.8 | 9.9±4.6 | −1.7 (−2.4 to −1.0)* | −2.7 (−4.3 to −1.0)* |
HRpeak,beat/min | 146.9±21.1 | 152.4±21.3 | 137.4±18.0 | 127.5±18.6 | −9.5 (−12.8 to −6.1)* | −24.9 (−40.2 to −9.5)* |
Haemoglobin, g/dL | 14.7±1.6 | 14.2±1.8 | 13.9±1.3 | 13.6±2.4 | −0.7 (−1.1 to −0.2)* | −1.1 (−2.4 to −0.3) |
Data are presented as mean±SD; for pulmonary function, n=63 4–6 weeks after surgery.
*Change from baseline is significant at the 0.01 level
DLCO, carbon monoxide lung diffusion capacity; FEV1, forced expiratory volume after 1 s; HRpeak, peak heart rate; SpO2, oxygen saturation; VEpeak, peak minute ventilation; V̇O2peak, peak oxygen uptake.