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Blood vessels in the bone lack basement membrane. (A) Sagittal section of humerus from mouse embryo immunostained for EMCN and for BM markers collagen type IV, laminin and fibronectin. (B,C) Magnifications of the boxed areas in A show muscle and bone at E15.5 and E16.5. Unlike in muscle, blood vessels in bone tissue have no underlying BM. Scale bars: 100 µm in A; 15 µm in B,C.
