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Effect of L-leucine on toxicity of SOD1 overexpression in C. elegans. (A) A thrashing assay was carried out to assess motor neuron activity in C. elegans control (N2) or overexpressing SOD1 (SOD1) over the time course indicated. The thrashing assay was conducted in C. elegans overexpressing SOD1 grown on media containing L-leucine supplemented at 1, 2 or 5 mg/ml as indicated. Error bars represent standard deviation; **P<0.01.
