Table 2.
Characteristics of CTN Trials
| CTN Trial No. |
Sample Size (N) |
Intervention Type | Number of Deaths |
Total Observed Risk Time (Person Years) |
Average Years Per Person |
Crude Mortality Rate (per 100,000 PY) |
Primary drug of use (not reported if less than 1%) |
|---|---|---|---|---|---|---|---|
|
NIDA- CTN- 0001 |
113 | Pharmacological | 2 | 48.19 | 0.43 | 4150 | Opioids: 96% Multi- drug/substance/alcohol: 3% |
|
NIDA- CTN- 0002 |
230 | Pharmacological | 0 | 86.81 | 0.38 | 0 | Opioids: 99% |
|
NIDA- CTN- 0003 |
516 | Pharmacological | 3 | 100.58 | 0.19 | 2983 | Opioids: 84% Unknown: 15% |
|
NIDA- CTN- 0004 |
461 | Psychosocial/Behavior | 2 | 133.65 | 0.29 | 1497 | Alcohol: 28% Stimulants: 27% Other drug: 20% Cannabis: 15% Opioid: 9% |
|
NIDA- CTN- 0005 |
423 | Psychosocial/Behavior | 0 | 92.27 | 0.22 | 0 | Alcohol: 48% Stimulants: 26% Cannabis: 20% Opioid: 5% Other drug: 1% |
|
NIDA- CTN- 0006 |
454 | Psychosocial/Behavior | 0 | 183.53 | 0.40 | 0 | Stimulants: 57% Multi- drug/substance/alcohol: 30% Alcohol: 7% Cannabis: 2% Opioid: 2% No problem: 1% |
|
NIDA- CTN- 0007 |
403 | Psychosocial/Behavior | 1 | 187.00 | 0.46 | 535 | Opioid: 40% Stimulant: 34% Multi- drug/substance/alcohol: 22% Unknown: 2% |
|
NIDA- CTN- 0009 |
225 | Pharmacological and Psychosocial/Behavior |
1 | 108.30 | 0.48 | 923 | Opioid: 52% Stimulants: 17% Multi- drug/substance/alcohol: 11% Cannabis: 8% Alcohol: 7% Other drug:4% No problem: 1% |
|
NIDA- CTN- 0010 |
154 | Pharmacological | 1 | 113.45 | 0.74 | 881 | Opioids: 89% Multi- drug/substance/alcohol: 10% |
|
NIDA- CTN- 0011 |
339 | Psychosocial/Behavior | 2 | 86.82 | 0.26 | 2304 | Multi- drug/substance/alcohol: 45% Alcohol: 23% Stimulants: 21% Opioid: 7% Cannabis: 3% |
|
NIDA- CTN- 0013 |
200 | Psychosocial/Behavior | 0 | 64.75 | 0.32 | 0 | Stimulant: 31% Cannabis: 31% Opioids: 14% Multi- drug/substance/alcohol: 12% Alcohol: 11% Other drug: 2% |
|
NIDA- CTN- 0014 |
482 | Psychosocial/Behavior | 6 | 466.01 | 0.97 | 1288 | Cannabis: 45% No problem: 30% Multi- drug/substance/alcohol: 18% Stimulant: 4% Alcohol: 2% |
|
NIDA- CTN- 0015 |
353 | Psychosocial/Behavior | 4 | 401.89 | 1.14 | 995 | Multi- drug/substance/alcohol: 64% Stimulant: 19% Alcohol: 9% Opioid: 4% Cannabis: 3% |
|
NIDA- CTN- 0017 |
632 | Psychosocial/Behavior | 5 | 294.76 | 0.47 | 1696 | Multi- drug/substance/alcohol: 80% Opioid: 14% Stimulant: 6% |
|
NIDA- CTN- 0018 |
594 | Psychosocial/Behavior | 7 | 327.59 | 0.55 | 2137 | Multi- drug/substance/alcohol: 49% Stimulant: 16% Opioid: 14% Alcohol: 11% No problem: 5% Cannabis: 4% Other drug: 2% |
|
NIDA- CTN- 0019 |
515 | Psychosocial/Behavior | 5 | 296.68 | 0.58 | 1685 | Multi- drug/substance/alcohol: 42% Opioid: 23% Stimulant: 22% Alcohol: 5% No problem: 4% Cannabis: 2% Other drug: 2% |
|
NIDA- CTN- 0020 |
628 | Psychosocial/Behavior | 2 | 304.69 | 0.49 | 656 | Multi- drug/substance/alcohol: 51% Opioid: 23% Stimulant: 10% Alcohol: 10% No problem: 4% Cannabis: 2% |
|
NIDA- CTN- 0021 |
436 | Psychosocial/Behavior | 0 | 127.46 | 0.29 | 0 | Alcohol: 61% Stimulants: 25% Cannabis: 8% Opioid: 6% |
|
NIDA- CTN- 0028 |
303 | Pharmacological and Psychosocial/Behavior |
0 | 103.55 | 0.34 | 0 | Cannabis: 88% Alcohol: 8% Stimulant: 2% Unknown: 2% |
|
NIDA- CTN- 0030 |
653 | Pharmacological and Psychosocial/Behavior |
2 | 312.73 | 0.48 | 640 | Opioid: 91% Multi- drug/substance/alcohol:9% |
|
NIDA- CTN- 0031 |
471 | Psychosocial/Behavior | 0 | 234.81 | 0.50 | 0 | Stimulant: 55% Multi- drug/substance/alcohol: 37% Alcohol: 3% Cannabis: 2% Opioids: 2% |
|
NIDA- CTN- 0032 |
1281 | Psychosocial/Behavior | 6 | 654.46 | 0.51 | 917 | Alcohol: 32% Cannabis: 21% Opioid: 17% Stimulant: 13% No problem: 10% Other drug: 4% |
All CTN trials have group counseling as the standard of care (referred to as Treatment as Usual, TAU) of the CTPs, which is separate from “psychosocial” intervention indicated in this table.