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. Author manuscript; available in PMC: 2017 Oct 1.
Published in final edited form as: Semin Roentgenol. 2016 May 30;51(4):317–333. doi: 10.1053/j.ro.2016.05.016

Figure 3.

Figure 3

(A–C) Enhancement curves with signal intensity plotted against time. Red line: abdominal aorta. Red dashed line: hepatocellular carcinoma (HCC). Green line: portal vein. Purple line: hepatic vein. Blue line: hepatic parenchyma. Red shadow: arterial phase. Green shadow: portal phase. Gray shadow: delayed-transitional phase. Blue shadow: hepatospecific phase. (A) Enhancement curves with extracellular or interstitial CM. Hepatocellular carcinoma has late arterial enhancement. During portal and venous phase, the HCC washout is evident (HCC signal is lower than liver parenchyma). After the late venous phase, vascular and parenchymal signals decrease because of renal excretion. (B) Enhancement curves with Gd-EOB-DTPA. The enhancement peak of HCC tends to be lower than that of other CM. The rapid hepatocellular uptake results in increasing liver signal until a plateau at 20 minutes, whereas vascular signals tend to decrease rapidly. (C) Enhancement curves with Gd-BOPTA. The hepatospecific phase is after 60 minutes, and vascular signals decrease earlier than in (B). (Color version of figure is available online.)