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. Author manuscript; available in PMC: 2017 Oct 1.
Published in final edited form as: Semin Roentgenol. 2016 May 30;51(4):317–333. doi: 10.1053/j.ro.2016.05.016

Figure 4.

Figure 4

Focal nodular hyperplasia, evaluation with Gd-BOPTA and Gd-EOB-DTPA. A 50-year-old man with focal nodular hyperplasia (FNH). Axial 3D SPGR fat suppressed (LAVA, slice thickness or overlay: 4 mm/2 mm). Images acquired in the arterial phase (A and B), portal venous phase (C and D), and hepatobiliary phase (E and F), after the administration of Gd-BOPTA (A, C, and E) and Gd-EOB-DTPA (B, D, and F) in 2 different examinations. Typically, FNH are hyperenhancing in the arterial phase (A and B) with active uptake of CM in the hepatospecific phase (E—90 minutes since injection of Gd-BOPTA; F—20 minutes since injection of Gd-EOB-DTPA). (F) The rapid hepatocellular uptake of Gd-EOB-DTPA, together with renal elimination, results in hypointensity of intrahepatic vascular structures, visible as hypointense spot scattered in hepatic parenchyma. LAVA, liver acquisition volume acceleration.