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. 2016 Nov 21;9:84. doi: 10.1186/s13039-016-0294-0

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Refined karyotype of abnormal metaphase displayed in Fig. 3a with co-localized FISH signals indicated a hypodiploid clone with 1) a der(3)t(3;20)(p11.2;q11.2)(D20S108+); 2) a der(5)t(5;22)(q32;q11.2)(WCP22+); 3) a del(9)(p13)(CDKN2A-), a dic(9;17)(p13;p11.2)(D9Z1+,CDKN2A-;D17Z1+,TP53-,WCP17+); 4) a t(12;21)(p13;q22)(RUNX1+; ETV6+,RUNX1+) and add(21)(RUNX1+++++); 5) a der(14)t(14;17)(p11.2;q11.2)(WCP17+); 6) a der(17)t(17;22) (TP53+,D17Z1+,WCP17+,WCP22+); 7) der(22)t(5;22)(CSF1R+,WCP22+)