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. 2016 Nov 21;10:37. doi: 10.1186/s40246-016-0095-x

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 7 — Both cell growth and cell death are altered in ADPKD. NC-ADPKD cells have higher-than-normal expression and C-ADPKD cells have lower-than-normal expression of genes from ‘cell growth’ gene sets. Both NC-ADPKD and C-ADPKD cells have higher-than-normal expression of genes from ‘cell death’ gene sets. We present data as mean ± s.e.m., **P < 0.01, *P < 0.05 (black asterisk is in comparison to NK, gray asterisk is in comparison to NC-ADPKD). Cell Growth Gene Sets: (1) KEGG_CELL_CYCLE, (2) CELL_CYCLE, (3) CELL_CYCLE_CHECKPOINT, (4) CELL_CYCLE_PROCESS, (5) CELL_CYCLE_PHASE, (6) MITOTIC_M_PHASE, (7) MITOTIC_CELL_CYCLE, (8) M_PHASE, (9) MITOSIS. Cell Death Gene Sets: (10) KEGG_APOPTOSIS, (11) APOPTOTIC_PROCESS, (12) PROGRAMMED_CELL_DEATH