Table 8.
Haplotype analysis of TPH-2 between two groups
| Haplotype distribution | Case (freq) | Control (freq) | χ 2 | Fisher P | OR [95% CI] |
|---|---|---|---|---|---|
| SNP1-2 | |||||
| G-A | 1.52 (0.007) | 10.57 (0.042) | 6.281 | 0.012233* | 0.149 [0.027–0.826] |
| T-A | 40.48 (0.174) | 24.43 (0.098) | 6.083 | 0.013679* | 1.951 [1.140–3.341] |
| SNP1-2-3 | |||||
| G-A-G | 1.51 (0.007) | 10.51 (0.042) | 6.234 | 0.012562* | 0.149 [0.027–0.831] |
| T-A-G | 38.73 (0.167) | 24.00 (0.096) | 5.409 | 0.020075* | 1.896 [1.099–3.272] |
| SNP1-2-4 | |||||
| T-A-A | 22.24 (0.096) | 10.60 (0.042) | 4.981 | 0.025669* | 2.315 [1.088–4.927] |
| SNP1-2-3-4 | |||||
| T-A-G-A | 21.77 (0.094) | 7.79 (0.031) | 8.031 | 0.004617* | 3.187 [1.376–7.382] |
SNP1:rs4570625; SNP2:rs11178997; SNP3:rs1386494; SNP4:rs7305115 * P<0.05