Fig. 2.

Meta-analysis of MSCs and related cell types. a Sample-to-sample heatmap of 264 microarrays that includes mesenchymal and hematopoietic lineage cells. Clustering of samples relies upon Euclidean distances derived from the pairwise calculation of the Pearson correlation between the expression vectors of each sample. In the right panel: the hematopoietic lineage samples are shaded in red and mesenchymal lineage samples are in yellow. The colour scale represents shorter to larger distance: from dark red to dark blue. b 3D plot of PCA based on the gene expression of the stromal and hematopoietic cells studied. Each dot represents a sample microarray from the repertoire of 264 and includes the global gene expression for each sample. c Biplot of PCA performed by genes of the same data. Samples are represented as arrow vectors in the derived PCA space on the Biplot