Table 3.

Tissue specific gene signatures: list of genes appearing differentially expressed in each tissue-MSC and fibroblasts when contrasted to each other

Tissue-stromal cells	Number of genes	Specific genes
AD-MSC	9	AC104654.2, AP000695.2, AP000843.1, MATN3, MFAP3L, PCDH9, PDLIM3, PPAPDC1A, Z69713.1
BM-MSC	37	ACAN, AGT, ANK3, AP001422.1, C20orf103, C20orf197, C5orf23, CHRDL1, CXCL16, DLX5, ENTPD1, EPHX1, EYA1, EYA2, EYA4, FBXO16, FMO3, HEY2, IGF2, IGFBP2, ITGA7, JAG1, KCNMB1, KIAA1217, KLHL3, LBP, LEPR, MAOB, NOTCH3, NPR3, RP11-145A3.3, SFTA1P, SLPI, TM4SF20, VCAM1 (CD106), ZNF423
PL-MSC	123	AC003092.2, AC012409.1, AC026250.2, AC069155.1, AC090625.2, ADAM23, ADRA1D, AL121578.3, ALDH1A1, ALDH1A2, AMIGO2, ANO4, AR, ATRNL1, BRIP1, C10orf57, C12orf59, C16orf52, C3orf72, C9orf167, CACNA1H, CADPS2, CAMK1G, CAPN6, CARD16, CKS2, CNTN4, CTSH, CYTSB, DGKH, DNAM1 (CD226), DTNA, E2F7, ETV4, F2RL1, FABP4, FAM105A, FAM155A, FAM60A, FJX1, GAS2L3, GBP4, GCLC, GLRXP3, GPR126, GPR37, HMGA2, HOXD10, HSD17B2, HTR1D, HTR2B, IFIT2, IFIT3, INA, KCNA3, KRT19, LAMA1, LCP1, LIMS1, LPCAT2, LRRC1, MAP3K5, MAPK8, MCTP1, MSI2, MUM1L1, NCAM1 (CD56), NEFM, NETO2, NID1, NNAT, NR2F1, PAMR1, PCDH10, PDCD1LG2, PDGFC, PLAT, PLBD1, PLCXD3, PMAIP1, RARB, RASGRP1, REN, RP11-117P22.1, RP11-251 J8.1, RP11-332P22.1, RP11-548O1.1, RP11-87H9.2, RP4-706A16.2, RPS6KA6, S1PR3, SCN9A, SERPINB2, SGIP1, SLC16A4, SLC1A2, SLC4A8, SLITRK4, SNCA, SNCAIP, SNORD27, SOCS1, SORBS1, SOX5, SSTR1, ST6GALNAC5, STRA6, SYPL2, SYT14, SYT16, SYTL5, TFPI2, TMEM154, TMEM51, TNFSF15, TNFSF18, TNFSF4, TRHDE, TRPC4, ZNF516, ZNF804A
FIB	60	AC008440.2, AC112217.2, ADAM33, ADH1B, AIM1, AK5, APCDD1, APOD, AQP9, BMPER, C9orf21, CCBE1, CCDC102B, CCRL1, CDON, CH25H, CLIC2, COLEC12, CYP7B1, DKK2, DNM1, GLDN, GLI3, GRPR, GTSF1, IGSF10, KIAA0802, KIT, LRRC15, MASP1, MBNL3, MMP27, OMD, OR1H1P, OR1Q1, OSR2, PAX3, PDGFRL, PHACTR3, PLEKHG1, PLXNC1, PRLR, RCAN2, ROBO2, RP11-392O17.1, RXFP1, SECTM1, SEMA3D, SIPA1L2, SLC9A9, STK32B, SVIL, TDO2, TFAP2C, TGFBR3, THBS4, THRB, TWIST1, TWIST2

Gene symbols in bold correspond to relevant genes that are commented in the discussion