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The haplotypic association of the four SNPs of the DARS gene with VSD
| Haplotypea | Case (%) | Control (%) | OR (95% CI) | P |
|---|---|---|---|---|
| GGA | 712(42.33) | 2551(43.19) | 1.00(referent) | |
| GGG | 562(33.41) | 1893(32.05) | 1.06(0.94-1.21) | 3.35 × 10-1 |
| AAG | 94(5.59) | 289(4.89) | 1.17(0.91-1.49) | 2.24 × 10-1 |
| GAG | 90(5.35) | 248(4.20) | 1.30(1.01-1.68) | 4.30 × 10 -2 |
| AGA | 140(8.32) | 681(11.53) | 0.74(0.60-0.90) | 3.00 × 10 -3 |
| Others | 84(4.99) | 244(4.13) | 1.23(0.95-1.60) | 1.15 × 10-1 |
aSNP order: rs2164331, rs6738266, rs309143
