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Combined effects of rs2164331, rs6738266, and rs309143 on isolated VSD
| Number of risk allelesa | Case (%) | Control (%) | OR (95% CI)b | P b |
|---|---|---|---|---|
| 0-2 | 231 (27.47) | 949 (32.14) | 1.00 | |
| 3 | 68 (8.08) | 276 (9.35) | 1.01(0.75-1.37) | 9.37 × 10-1 |
| 4 | 361 (42.93) | 1219 (41.28) | 1.22 (1.01-1.47) | 3.8 × 10-2 |
| ≥5 | 181(21.52) | 509(17.24) | 1.46(1.17-1.83) | 1.0 × 10-3 |
| Trend | 6.37 × 10-4 |
ars2164331 A, rs6738266 A, rs309143 G were assumed as risk alleles
bCalculated by additive model
