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. 2016 Nov 21;17:181. doi: 10.1186/s12882-016-0395-3

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Expansion of TCR repertoire at the time of graft rejection. We generated the recurrent TCR repertoire by combining all TCR clones appeared at any time point (before and after transplant) in samples obtained from blood or graft. And then compared the frequency of each clone in the recurrent repertoire at the time of rejection (or the same time in case of patients with no rejection) with that at the earliest time point available for analysis (before transplant or 1 month post transplant)