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. 2016 Nov 21;17:181. doi: 10.1186/s12882-016-0395-3

Table 2.

Clinical characteristics of all seven patient with TCMR

ID Age, Y Gender Race Type of transplant Cause of ESRD cPRA DSA Induction Time to rejection (months) Type of TCMR Reason for rejection
1 60–65 Male African American DDRT HTN 0 DR53
Flowcytometric cross match level
Thymoglobulin 19 2A BK viremia/lower immunosuppression
2 30–35 Male White DDRT Diabetic nephropathy 0 De novo DQA5
Below flowcytometric crossmatch
Thymoglobulin 11 1A Lower dose of MMF
3 20–25 Female White LRT IgA nephropathy 0 De novo DSA: DR7, DR53, DQA3, DQB2, and DQB7 positive cytotoxic crossmatch Thymoglobulin 21 1B
4 40–45 Female White LRT Lupus nephritis 9% Negative Thymoglobulin 1 1A Lower dose of MMF
5 45–50 Female Asian LRT Unclear Etiology 10% Negative IL2 antagonist 3 1A
6 55–60 Female Asian DDRT Chronic glomerular nephropathy 0 Negative IL2 antagonist 3 1A
7 40–45 Female Asian LRT Diabetic nephropathy 70% Negative IL2 antagonist 35 1A

cPRA calculated Panel Reactive Antibodies, DSA Donor Specific Antibodies, TCMD T cell mediated rejection, DDRT deceased donor renal transplant, HTN hypertension, MMF mycophenolate mofetil, LRT living donor renal transplant