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. 2016 Nov 21;13:81. doi: 10.1186/s12977-016-0312-7

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© The Author(s) 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Differential binding of JRFL and JRCSF to CD4-bs-directed bNAbs b12 and VRC01. FACS-based cell surface staining assay was used to measure binding of a glycan-dependent antibody 2G12, b, c CD4-bs-directed bNAbs b12 and VRC01, and d, e CD4-bs-directed non-NAbs F105 and b6 to JRFL and JRCSF over a range of antibody concentration