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. 2016 Nov 21;16:907. doi: 10.1186/s12885-016-2933-6

Table 2.

Dose escalation scheme

Dose Level PEP02 (mg/m2) No. patients No. patients with DLT
I 60 3 0
II 80 3 + 3 0 + 0
III 100 3 + 2 0 + 2
IV 120 2 2

Abbreviation: DLT dose-limiting toxicity