Table 4.
The effect of H. odorata extracts on intestinal transit in mice using charcoal meal as a marker
| Treatment/Dose | % of intestine cross by marker | % of inhibition |
|---|---|---|
| Saline | 84.85 ± 2.88 | |
| Loperamide | 45.35 ± 1.72a | 43.6 ± 2.14 |
| MEHO200 | 59.89 ± 0.51b | 25.63 ± 0.63 |
| MEHO400 | 52.72 ± 1.11b | 34.43 ± 1.38 |
| EEHO200 | 57.15 ± 0.81b | 28.1 ± 1.01 |
| EEHO400 | 51.51 ± 0.97b | 35.93 ± 1.21 |
| AEHO200 | 62.05 ± 1.41b | 22.82 ± 1.76 |
| AEHO400 | 55.04 ± 1.54b | 31.54 ± 1.91 |
Values are presented as mean ± SEM for 5-6 rats. Data for % of intestine cross by H. odorata extracts, positive antidiarrheal control (Loperamide, 5 mg/kg p.o.) and normal control (saline) were processed by paired t-test analysis using Statistical package for social Science (SPSS for windows, version 21.0, IBM Corporation, New York, USA) followed by Dunnet test. a & b superscript letters are statistically significant to each other. Values with P < 0.05 are considered as statistically significant