Table 5.

Comparison of the previously reconstructed models [21] with the new models produced by CoReCo in this article

CoReCo model	T. reesei		S. cerevisiae		Average of all modelsa
	Pitkänen [21] (%)	This article (%)	Pitkänen [21] (%)	This article (%)	Pitkänen 21] (%)	This article (%)
Dead end reactions	58	44	61	44	59	44
Dead end metabolites	68	59	70	58	69	58
Reactions added during the gap-filling step	37	20	35	22	39	21
Biomass components produced	7	100	7	100	7	89
Biomass components produced*	98*	100	100*	100	91*	89
Biomass components produced with stoichiometrically unrealistic yield	98*	0	64*	0	85*	0

* When eight extra compounds were added as a source metabolites into the model simulations

^a The obligate intracellular parasite Encephalitozoon cuniculi has been excluded from the averages