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. Author manuscript; available in PMC: 2017 Oct 20.
Published in final edited form as: Cell. 2016 Oct 13;167(3):695–708.e16. doi: 10.1016/j.cell.2016.09.035

Figure 4. Large-Scale Patterns of DSB Formation and Recombination.

Figure 4

(A,B) Per unit length, smaller autosomes incur more DSBs (A) and crossovers (B, centimorgans [cM]; data from Froenicke et al., 2002). SPO11-oligo density was exceptionally low in the non-PAR segments of the sex chromosomes, but very high in the PAR. The crossover rate in the PAR was set at 50 cM.

(C) The greater crossover density on smaller autosomes is explained only in part by the higher SPO11-oligo density.

See also Figure S4 and Table S5.